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Atropine ophthalmic may also be used for purposes other than those listed in this medication guide. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. Atropine ophthalmic can pass into breast milk and may harm a nursing baby.
Tell your doctor if you are breast-feeding a baby. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine. Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated dropper or tube tip can infect your eye, which could lead to serious vision problems.
Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use. Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication. Seek emergency medical attention or call the Poison Help line at if you have used too much atropine ophthalmic, or if anyone has accidentally swallowed the medication.
Cognitively Normal Elderly : In cognitively normal elderly adults e. Activated charcoal in patients with intact mental status or secure airway who have likely ingested an anticholinergic agent. Physostigmine has been recommended for reversal of anticholinergic toxicity when patients exhibit both peripheral and central anticholinergic toxicity e. Physostigmine is a carbamate anticholinesterase that reversibly inhibits acetylcholinesterase, resulting in an elevated concentration of acetylcholine in the synaptic cleft of cholinergic nerve endings.
This can reverse the effects of antimuscarinic drugs at these locations. It is a tertiary amine that can cross the blood-brain-barrier, resulting in a reversal of both central and peripheral effects of anticholinergic agents. The patient should be placed on a cardiac monitor, with atropine and resuscitative equipment available before physostigmine is given.
The half-life of physostigmine is 15 minutes, but its effects last significantly longer; additional smaller doses may need to be given if agitated delirium reoccurs. Most patients don't require physostigmine for more than hours after the initial dose.
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